
Anti-aging night serum · Coming soon
PDRN + Retinol Night Serum
Moisture barrier support · 30 mL (1 fl oz)
An anti-aging night serum that pairs PDRN with retinol in a comforting serum-lotion texture. It works while you sleep to soften the look of fine lines, smooth rough texture and leave skin looking plump and rested by morning.
- Softens the look of fine lines and wrinkles
- Smooths the look and feel of rough texture
- Plumps skin with hydration for a firmer, fuller look
- Serum-lotion texture with moisture barrier support
Launching soon. Price and where to buy go to the waitlist first.
What you’ll see
Made for the morning after.
Softer-looking lines
Retinol, the classic night-routine ingredient, smooths the look of fine lines and wrinkles.
A firmer, fuller look
Moisture-binding ingredients plump skin with hydration, so it looks bouncier and firmer.
Smoother texture
Rough, uneven patches look and feel more refined, night after night.
A rested glow
Wake up to skin that looks bright, even and well-rested.
Inside the formula
Two night-care favorites, one comforting texture.
PDRN
A DNA-derived ingredient from Korean skincare, loved for the bouncy, glassy finish it gives skin.
What is PDRN?Retinol
The gold standard of night care for smoothing the look of fine lines and uneven texture.
Retinol for beginnersBarrier support
A comforting serum-lotion that helps skin hold on to moisture overnight, so retinol feels easy to live with.
Retinol and your barrier
We’ll publish the full ingredient list here and on the box at launch.
How to use
One step, at night.
- Step 1: Cleanse at night and pat skin dry.
- Step 2: Smooth a pea-size amount over face and neck.
- Step 3: Start every other night, then build to nightly. Wear sunscreen in the morning.
New to retinol? Our retinol for beginners guide walks through a gentle starter schedule.
Good to know
- Patch test first: try a small amount along your jawline for a few nights before using it on your whole face.
- Retinol can make skin more sensitive to the sun. Wear a broad-spectrum sunscreen, SPF 30 or higher, every morning.
- Skip retinol if you're pregnant or breastfeeding, and ask your doctor if you're trying to conceive.
- Avoid the eye area, and don't apply to broken or irritated skin.
- Stop use if discomfort continues, and talk with your doctor.
What does the PDRN + Retinol Night Serum do?
It works overnight to soften the look of fine lines and wrinkles, smooth rough texture and leave skin looking plump, firm and rested by morning. Its serum-lotion texture is made with moisture barrier support in mind.
Where does your PDRN come from?
We'll confirm the source on the full ingredient list at launch. If you have a fish allergy, check that list and ask your doctor before trying it.
What's the full ingredient list?
We'll publish the complete ingredient list here and on the box at launch.
How often should I use a retinol serum?
Start two nights a week. After a couple of weeks, move to every other night if your skin feels comfortable, then build up from there. Use it at night on clean, dry skin and follow with moisturizer.
Can I use it with vitamin C or exfoliating acids?
Keep them apart while you get used to retinol. Use exfoliating acids on different nights, and move vitamin C to your morning routine.
Can I use retinol while pregnant or breastfeeding?
The American Academy of Dermatology advises avoiding retinoids, including retinol, during pregnancy. If you're pregnant, trying to conceive or breastfeeding, ask your doctor before using any retinol product.
Learn
Go deeper.

Routines
PDRN and retinol together
Yes, PDRN and retinol can share a night routine. How to layer them, which goes first, how often to start and what else pairs well for comfortable skin.
3 min read

Ingredients
Retinol for beginners
New to retinol? How often to use it, how much to apply, what to pair it with and how to keep skin comfortable while you build up. A simple starter plan.
3 min read

Ingredients
What is PDRN?
PDRN (polydeoxyribonucleotide) is the DNA-derived ingredient behind K-beauty's salmon serum trend. What it is, where it comes from and how to use it.
3 min read
Skincare worth falling for.
Join the waitlist and we’ll email you the day Lemerence launches.